The Holiday Inn® Hotel and Conference Center in Alton Illinois is where guests choose to stay (ALL GUEST ROOMS NON SMOKING) when they visit the Great River Road, Raging Rivers Water Park, Gordon Moore Park, Argosy Casino, Mississippi River, Bird Watching, Bald Eagles, Pelicans, Lewis & Clark Museum and Interpretive Center, Great Rivers Museum, Robert Wadlow Statue, Great Godfrey Maze, Pere Marquette State Park, Haunted Alton Tours, Die Laughing Dinner Theater, Golf Packages, Spencer T. Olin Arnold Palmer Golf Course, Belk Park, Fox Creek, The Woodlands, Timberlakes, Annbriar, and Stone Wolf Golf Courses, Antiques, Alton Marina, Gateway International Raceway, Premier Air, Olin Corporation, American Waterworks, Conoco Refinery, Vallero, BP Amoco, Lewis & Clark Community College, Principia College, SIU Dental School, SIU Edwardsville, St. Louis Cardinals Baseball, Rams Football, Blues Hockey, the Arch, Six Flags over Mid-America, and St. Louis Zoo. Minutes from I-55, I-255, or I-270, we are located at the intersection of Route 140 and Route 3. We are 30 minutes from Downtown St. Louis, 30 minutes from St. Louis Lambert International Airport, 15 minutes from St. Louis Regional Airport in Bethalto, IL, one half mile from Amtrak Station and 5 miles from Alton Marina and Argosy Casino. This hotel is committed to providing accessible facilities under the American Disabilities Act. If your accessibility needs are not met, please contact the Hotel Manager on Duty. Should you require additional information regarding accessible facilities for guests with disabilities, please call 1-800-465-4329 (U.S. and Canada) or contact the hotel directly. For the hearing impaired, TDD service is available at 1-800-238-5544 within the U.S. and Canada.