Our Anderson, South Carolina Hotel is the Smart Choice Directly off Interstate-85 at exit 19B, our newly renovated Holiday Inn Express® & Suites Anderson - I-85 hotel is near Clemson University, upstate businesses and attractions. We're the premier choice for leisure and business travelers in Anderson, SC. Our hotel is ideal for corporate travelers as we're minutes from companies like Michelin, Bosch, Plastic Omnium and Duke Power in Anderson, South Carolina. Our hotel's 24-hour business center lets you to catch up on work and our 672-sq ft Palmetto Room provides an ideal location for meetings. Our rooms offer a great work environment to stay productive while you're traveling. You can almost hear the cheering from Death Valley when the Clemson Tigers play. Not only is our hotel's location near Clemson University, but we're just six miles from Anderson University. In addition, you'll be close to Lake Hartwell, where you can enjoy fishing, boating and more. The SC Botanical Gardens are a great way to enjoy our scenic area. Few hotels near Greenville, SC can match the amenities that you'll find at our freshly updated Anderson, SC hotel. Our rooms are an oasis of comfort with either 32- or 37 inch flat panel TVs, microwaves and fridges. A free breakfast buffet starts your day right and you can enjoy our sparkling, outdoor pool, spa or Fitness Center. Make the smart choice with a stay at the best of Anderson, South Carolina hotels. This hotel is committed to providing accessible facilities under the American Disabilities Act. If your accessibility needs are not met, please contact the Hotel Manager on Duty. Should you require additional information regarding accessible facilities for guests with disabilities, please call 1-800-465-4329 (U.S. and Canada) or contact the hotel directly. For the hearing impaired, TDD service is available at 1-800-238-5544 within the U.S. and Canada.