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Holiday Inn Express & Suites BUFFALO DOWNTOWN - MEDICAL CTR

601 Main Street
Buffalo, NY 14203
Nightly Rates: ($186.50 - $186.50)
Hotel Information
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Map / Directions
Nearby Attractions

Hotel Description:

We welcome you to stay at our Holiday Inn Express & Suites Buffalo, located in the heart of downtown near Roswell Park, John R. Oishei Children's Hospital, Buffalo General Hospital, Convention Center and Canalside. Hotel parking is available nearby at additional charge in parking garage. Enjoy being nestled in the heart of the Theatre District, where you can experience a grand performance at Shea's Performing Arts Center or the Irish Classical Theatre. Take in a concert at the Town Ballroom or TRALF located within the same block or hop on the above ground trolley train to the Key Bank Center. The Seneca Buffalo Creek Casino offers a free shuttle to and from the casino. Buffalo Riverworks and the Buffalo Naval Park are also just a few blocks away. The city is also packed with events and festivals at Canalside and Sahlen's Field (home of the Buffalo Bisons). Admire contemporary art at the Albright-Knox Art Gallery or discover Frank Lloyd Wright's stunning residencies nearby and marvel at the Darwin Martin House. Don't forget to make the 20 mile trip to one of the Nation's North American Wonders of the World - Niagara Falls! For those traveling on business we are in close proximity to M&T Bank, Buffalo Niagara Medical Campus, and New Era Cap. You will appreciate our 24-hour business center and fitness center. Also located adjacent to the hotel is a TGI Fridays restaurant.

Check In:  3:00 PM
Check Out:  11:00 AM

Native currency:  American Dollars
Number of floors:  7
Number of rooms:  146
Number of suites:  146
Time zone:  GMT


TGI Friday's: We have a TGI Friday's attached to our hotel which is open Sunday through Thursday 11 am to 12 am and Friday and Saturday open 11am to 1am.


Fitness center on-site
Fitness center off-site
Childrens's program

Room Info:

Connecting rooms

Hotel Amenities:

(additional fees may apply to certain amenities)

  • ATM/Cash machine
  • Car rental desk
  • Desk with lamp
  • Grocery shopping service available
  • Housekeeping - weekly
  • Late check-out available
  • Non-smoking
  • Private bathroom
  • Satellite television
  • Spare electrical outlet available at desk
  • Wireless internet connection
  • Accessible facilities
  • Coffee/Tea maker
  • Direct dial telephone
  • Hairdryer
  • Ice machine
  • Meal included - continental breakfast
  • On-Site parking
  • Public area air conditioned
  • Separate closet
  • Sundry/Convenience store
  • Wireless internet connection in public areas
  • Air conditioning individually controlled in room
  • Color television
  • Dry cleaning
  • High speed internet connection
  • Interior corridors
  • Microwave
  • Onsite laundry
  • Restaurant
  • Shops and commercial services
  • Valet same day dry cleaning
  • Buffet breakfast
  • Complimentary newspaper in lobby
  • Golf
  • Housekeeping - daily
  • Ironing board
  • Mini-refrigerator
  • Parking
  • Safe deposit box
  • Sofa bed
  • Voice mail

Photo Gallery:


Sorry there are no virtual tours available for this hotel at this time.


Walden Galleria MallLarge shopping mall with department stores, movie theatres, Regal Cinemas and lots of restaurants.

Erice County Fair

75 Exchange St

75 Exchange St, Buffalo NY 14203


Buffalo Niagara International Airport

Diamond HawkWestern New York's premier golf course offering country club amenities at a public course. Located in the heart of Greater Buffalo Area.

Shea's Performing Arts CenterShea's Performing Arts Center is a theater for touring Broadway musicals and special events. It was opened in 1926 to show silent movies.

Buffalo Niagara Convention CenterThe convention center is the perfect location to host any meeting, convention, trade show or wedding. Located in the heart of downtown just 3 blocks from this hotel.

Key Bank CenterThe Key Bank Center, formerly know as First Niagara Center, is a multipurpose indoor arena located near the canalside. It is home to the Buffalo Sabres Hockey team and Buffalo Bandits professional lacrosse team. Capacity is around 19,000 people.

Canalside BuffaloCanalside is a historic redevelopment district that was once the western terminus of Erie Canal. Now it is a vibrant area with cultural events, festivals, concerts and more.

Seneca Buffalo Creek CasinoCasino owned by Seneca Nation of New York near the waterfront of downtown Buffalo. The complex has 67,000 square feet of gaming space and restaurants. Free shuttle to and from the hotel and casino during designated times.

Niagara FallsNiagara Falls is the ocollective name for three waterfalls that straddle the internatinal border between Canada and the United States. The three falls are the Horseshow Falls, the American Falls and the Bridal Veil Falls.

Buffalo Naval ParkMilitary Museum where guests can tour three naval vessels.

Buffalo ZooThe zoo opened in 1875 and is the third oldest zoo in the United States.

Albright-Knox Art GalleryArt museum for modern and contemporary art. The parent organization is the Buffalo Fine Arts Academy.

Darwin Martin HouseThe Darwin Martin House Complex was designed by Frank Lloyd Wright and built between 1903 and 1905. Tours available for the six house complex each day.

Buffalo & Erie County Botanical Garden

Sahlen's FieldHome of the Buffalo Bisons

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