A Gracious Hotel in North Charleston, SC Welcomes You The Holiday Inn Express Hotel North Charleston, SC welcomes you to the "friendliest city in the nation". Charleston is the ideal South Carolina vacation destination because it has everything, from deep-sea fishing, world-class golf and tennis, to museums and Spoleto. Leisure travelers appreciate our North Charleston hotel's convenient location and access to the city via I-26. Museum Mile, Fort Sumter, Rainbow Row and the historic district are only 18 miles away. Charleston Southern University is almost next-door. And while lodging in Charleston, SC at our hotel, you can step back in time by visiting nearby plantations. Our low-country hotel in North Charleston means business travelers are close to the Charleston Airport (CHS). The North Charleston Coliseum, Summerville, Goose Creek and Moncks Corner are convenient too. There's also a 24-hour business center and free high-speed Internet access. Charleston, SC is a gracious city and your stay at our smoke free hotel in North Charleston will be equally gracious. We offer the amenities you deserve from the original snapshots of the low-country to the scrumptious, hot breakfast buffet. You can enjoy a seasonal, outdoor pool and spacious rooms, some with Jacuzzis. This is the perfect lodging for everyone from families to groups. Stay Smart on your next visit to Charleston, South Carolina and enjoy great Charleston hotel deals today. This hotel is committed to providing accessible facilities under the American Disabilities Act. If your accessibility needs are not met, please contact the Hotel Manager on Duty. Should you require additional information regarding accessible facilities for guests with disabilities, please call 1-800-465-4329 (U.S. and Canada) or contact the hotel directly. For the hearing impaired, TDD service is available at 1-800-238-5544 within the U.S. and Canada.