The Best Western St. Charles Inn is one of historic St. Charles premier business class hotels. Beautifully decorated and loaded with amenities. Stroll through historic St. Charles with its many unique shops and restaurants or take a tour of our local wineries. The casinos provide daily entertainment or just relax at our hotel and let our courteous and professional staff ensure your stay will be one you will never forget.

·From: North. Take Highway 270 South to Highway 70 West. Cross over the Blanchett Bridge and take a right at 229B South Fifth Street Exit. At the first 4-way stoplight turn left onto Bass Pro Drive. At the first 4-way stop sign turn left. The Best Western St. Charles Inn is straight ahead. ·From: South. Take Highway 270 North to Highway 70 West. Cross over the Blanchett Bridge and take a right at 229B South Fifth Street Exit. At the first 4-way stoplight turn left onto Bass Pro Drive. At the first 4-way stop sign turn left. The Best Western St. Charles Inn is straight ahead. ·From: East. Take Highway 70 West. Cross over the Blanchett Bridge and take a right at 229B South Fifth Street Exit. At the first 4-way stoplight turn left onto Bass Pro Drive. At the first 4-way stop sign turn left. The Best Western St. Charles Inn is straight ahead. ·From: West. Take Highway 70 East to Exit 229B (South Fifth Street). Turn left and at the first 4-way stoplight turn left onto Bass Pro Drive. At the first 4-way stop sign turn left. The Best Western St. Charles Inn is straight ahead.