The Holiday Inn Express hotel is ideally located directly across the street from the University of South Dakota's, Dakota Dome, and three blocks from the main campus. This Vermillion hotel is minutes from the scenic Oyate Trail, the National Music Museum, the W.H. Over Museum, the Missouri River and Spirit Mound Historic Prairie. The University of South Dakota is home to many museums and sporting venues. Vermillion is home to a special blend of agriculture, higher education, retail business and light industry. Several shopping opportunities are minutes from the hotel. A variety of restarants and cocktail lounges are located in the surrounding area. Stay Smart at the Holiday Inn Express Vermillion. This hotel is committed to providing accessible facilities under the American Disabilities Act. If your accessibility needs are not met, please contact the Hotel Manager on Duty. Should you require additional information regarding accessible facilities for guests with disabilities, please call 1-800-465-4329 (U.S. and Canada) or contact the hotel directly. For the hearing impaired, TDD service is available at 1-800-238-5544 within the U.S. and Canada.