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<< Back We're sorry, there are no hotels located in Greenville, MO. Below is a list of the closest cities to Greenville that have hotels, along with their distance from Greenville: Poplar Bluff, MO - 25.6 miles from Greenville, MO Fredericktown, MO - 31.1 miles from Greenville, MO Ironton, MO - 34.2 miles from Greenville, MO Dexter, MO - 35.3 miles from Greenville, MO Doniphan, MO - 40.6 miles from Greenville, MO Farmington, MO - 45.2 miles from Greenville, MO Jackson, MO - 46.8 miles from Greenville, MO Sikeston, MO - 50.6 miles from Greenville, MO Perryville, MO - 52.1 miles from Greenville, MO Cape Girardeau, MO - 52.6 miles from Greenville, MO Marston, MO - 62.6 miles from Greenville, MO Change Destination / Dates  IHSAdvantage.com
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