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Seneca South Carolina Hotels

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Jameson Inn Seneca
226 Hi-Tech Road
Seneca, SC 29678
•  2.3  Miles From Center City Seneca
•  3 Star Hotel

Rooms From: $86.24
Featuring true Southern Hospitality, Legendary Service, white colonial design, Deluxe Breakfast, clean comfortable rooms, fitness center & sparkling pool. Close to area attractions... more
Days Inn Seneca/Clemson
11015 Radio Station Rd.
Seneca, SC 29678
•  1.9  Miles From Center City Seneca
•  3 Star Hotel

Rooms From: $69.96
Our motel is surrounded by lakes with the mountains nearby. There are numerous restaurants in the area, a cinema, shopping areas within walking distance and the hospital is only ... more
Best Western Executive Inn
511 US Highway 123 Bypas
Seneca, SC 29678
•  0.9  Miles From Center City Seneca
•  2 Star Hotel

Rooms From: $79.99
Find great customer service and amenities while staying at this full service Seneca, South Carolina hotel. Situated right off South Carolina's US Highway 123, the Best Western Exe... more
Country Inn & Suites By Carlson Anderson
116 INTERSTATE BOULEVARD
Anderson, SC 29621
•  15.5  Miles From Center City Seneca
•  3 Star Hotel

Rooms From: $107.10
Studio suites, one bedroom suites and whirlpool suites. All units feature wireless high speed Internet, microwave, refrigerator, in-room movies, iron/board, coffeemaker and hairdr... more
Americas Best Value Inn/Clayton
698 Hwy 441 South
Clayton, GA 30525
•  28.4  Miles From Center City Seneca
•  1 Star Hotel

Rooms From: $49.99
The Americas Best Value Inn, in Clayton, Georgia is located in the gateway to Rabun County, in North Georgia*s mountains vacation destination. Near Atlanta, GA and Greenville, SC. ... more
Knights Inn & Suites Toccoa
1101 South Big A Rd
Toccoa, GA 30577
•  21.2  Miles From Center City Seneca
•  1 Star Hotel

Rooms From: $66.00
Welcome to the Knights Inn and Suites of Toccoa, GA. Our Newly RENOVATED property is minutes from Toccoa Falls College and North Georgia Tech College is 3 miles from the Hotel. 2 M... more
Best Western Regency Inn & Suites
13705 Jones Street
Lavonia, GA 30553
•  19.0  Miles From Center City Seneca
•  2 Star Hotel

Rooms From: $69.99
Discover the Best Western Regency Inn & Suites, located just off Exit 173 of Interstate 85 on Highway 17 in Lavonia. We are close to everything, such as Emmanuel College, Lake Hart... more
Best Western Lake Hartwell Inn & Suites
1357 E Franklin Street
Hartwell, GA 30643-7132
•  22.9  Miles From Center City Seneca
•  2 Star Hotel

Rooms From: $80.99
Discover Best Western Lake Hartwell Inn & Suites located in Historic Hartwell, Georgia. Experience the hospitality and charm of the South in this "Main Street" City and the magnifi... more
Quality Inn Anderson
3025 North Main Street
Anderson, SC 29621
•  19.3  Miles From Center City Seneca
•  2 Star Hotel

Rooms From: $69.99
The Quality Inn is located near Historic Downtown Anderson, away from bustling Interstate traffic. Our location, conveniently situated within walking distance to Anderson Mall, is ... more
Best Western Piedmont Inn & Suites
70 Kalyns Way
Piedmont, SC 29673
•  28.4  Miles From Center City Seneca
•  2 Star Hotel

Rooms From: $66.99
Discover this brand new Piedmont, South Carolina hotel located minutes away from the BI-LO Center, downtown Greenville and Clemson University. Located just off Interstate 85 in N... more
Days Inn Anderson
1007 Smith Mill Rd.
Anderson, SC 29625
•  16.1  Miles From Center City Seneca
•  3 Star Hotel

Rooms From: $69.00
Our Anderson, South Carolina Hotel is the Smart Choice. Days Inn in Anderson, SC located directly off Interstate-85 and exit 19A, our hotel is near Clemson University and a number ... more
Super 8 Anderson/Clemson Area
3302 Cinema Ave.
Anderson, SC 29621
•  18.5  Miles From Center City Seneca
•  1 Star Hotel

Rooms From: $53.00
Welcome to the Super 8 in Anderson/Clemson, SC with easy access to Interstate 85 via exit 19A. We are in close vicinity to the shores of Hartwell Lake, Clemson University and Stad... more
Hampton Inn Highlands NC
Highway 106 and Spring Street
Highlands, NC 28741
•  29.2  Miles From Center City Seneca
•  2 Star Hotel

Rooms From: $165.00
The Hampton Inn Highlands hotel in Highlands North Carolina is located one block off Main Street on Hwy. 106 in the heart of the Blue Ridge Mountains. Visitors to Highlands North C... more
Hampton Inn Anderson
120 Interstate Blvd
Anderson, SC 29621
•  16.0  Miles From Center City Seneca
•  2 Star Hotel

Rooms From: $169.00
The Hampton Inn Anderson hotel is located by Lake Hartwell near Clemson University and major industries in South Carolina. It is also near Belton Honeapath Pendelton Williamston an... more
Hampton Inn Easley
8 Southern Center Court
Easley, SC 29640
•  26.1  Miles From Center City Seneca
•  2 Star Hotel

Rooms From: $89.00
The Hampton Inn Easley SC hotel is located just inside the city limits of Easley South Carolina. Our location is convenient to Easley Powdersville and Greenville SC. Whether trave... more
Courtyard Clemson
201 Canoy Lane
Clemson, SC 29631
•  8.1  Miles From Center City Seneca
•  3 Star Hotel

Rooms From: $99.00
When you travel near Clemson check in to the BRAND NEW Courtyard by Marriott located off of Hwy. 93 and US 123 , within a mile of Clemson University. Ideally situated between Atlan... more
Comfort Suites Anderson
118 Interstate Blvd.
Anderson, SC 29621
•  15.9  Miles From Center City Seneca
•  3 Star Hotel

Rooms From: $149.99
Great location just off I-85 at exit 19B. Located only 8 miles from Clemson University. We offer FREE Wireless High-Speed Internet Access, deluxe continental breakfast featuring ... more
Americas Best Value Inn-Anderson
4020 Clemson Blvd.
Anderson, SC 29621
•  17.5  Miles From Center City Seneca
•  2 Star Hotel

Rooms From: $49.95
Welcome to the Americas Best Value Inn of Anderson, South Carolina. We are conveniently located just 1 1/2 miles south of I-85 at exit 19A along US Hwy 76. Our 2-story property Inn... more
Holiday Inn ANDERSON
3509 CLEMSON BLVD
Anderson, SC 29621
•  18.0  Miles From Center City Seneca
•  2 Star Hotel

Rooms From: $167.00
We invite you to experience the brand new Holiday Inn Anderson Clemson area the newest full service Anderson hotel!Easily accessed from I-85 at exit 21 (Liberty Highway). Only a fe... more
Ramada Clemson
U.S. Highways 76 and 123
Clemson, SC 29631
•  7.4  Miles From Center City Seneca
•  2 Star Hotel

Rooms From: $59.01
The Ramada of Clemson, SC is located at the intersection of Highway 76 & 123 and is the Clemson areas only full service hotel. The South Carolina Botanical Gardens and T. Ed Garris... more
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•  Many Seneca South Carolina hotels that allow pets require a fee for doing so, while others do not.   If you are booking a room at a pet friendly hotel in Seneca, South Carolina, call the hotel before your arrival to see what terms and conditions may apply.

•  Paying for your Seneca hotel reservation before your stay can be a huge money-saver.  Most hotels in Seneca are willing to lower their rates for guests who purchase in advance.

•  Are you under the age of 18? If so, you will need to check the hotel policy before booking your room. Some Seneca hotels are ok with the age 18 and above staying alone, but other hotels will not allow you to stay by yourself unless you have an adult with you.


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